康寧96孔盤用電極(EVOM2跨膜電阻儀專用)

Manual Electrode for EVOM2, Use with Corning HTS 96-Well Plate

型號：STX100C96

為加快藥品研發，發展出高通量(HTS, High Throughput Screening) protocol，多家主要的細胞培養杯製造商針對HTS引入新系列的細胞培養過濾盤。這些HTS孔盤通常有24或96獨立細胞培養杯結合成單一孔盤，便於機器人裝置處理。WPI針對這些新產品系，開發出自動REMS系統和手動電極來搭配。

提升TEER測量精確度

STX100採用和STX2電極相同的可靠設計原理，並做數個重要的修改。電極尖端尺寸減少至1.5mm以便於通過HTS孔盤較窄的隙縫。STX100電極本身採用更強的材質，耐用度更高、最大化可應用範圍。電極底部形狀設計為可完全貼合『鑰匙孔』狀的過濾杯，此種設計讓STX100電極相較於STX2電極，TEER讀數的精度和再現性提升±5歐姆。可以直接在HTS孔盤置於一般或分開的托盤上進行測量，減少汙染可能性並減少對培養細胞的的機械損傷。

 兼容以下Coring HTS孔盤：

Use in HTS

With the development of a High Throughput Screening (HTS) protocol for faster drug discovery, a new line of cell culture filter plates have been introduced by several major cell culture insert manufacturers. These HTS plates normally have either 24 or 96 individual cell culture inserts “bonded” together as one plate so that it can be handled by a robot apparatus. In response to these developments, WPI has developed an automatic REMS system and a manual electrode to go with it.

Increase accuracy of TEER measurements

STX100’s design is based on the same reliable design principle as the universally used STX2 electrode, with several important modifications. The size of the electrode tip has been reduced to 1.5 mm to facilitate positioning through the narrower slit of the HTS plate. The STX100 electrode itself is constructed using a stronger material for higher durability and maximum usage applications. The bottom section of the electrode is shaped to fit neatly into the “keyhole” shaped filter well. This enables the STX100 electrode to produce increased accuracy and reproducibility of TEER readings (±5 ohms) compared to the standard STX2. Measurement can be directly performed when the HTS plate is in either a common or divided tray, reducing the possibility of contamination as well as mechanical damage to the cultured cells.

This electrode is compatible with the following Corning plates: