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一般財団法人 動物繁殖研究所

小鼠 / Mouse

TSOD® (代謝症候群模式動物/Metabolic syndrome model animal)

TSNO® (對照組動物/Control of TSOD®)

源起

TSOD®小鼠源自於Doken有限公司的ddY小鼠。1984年時,偶然在ddY小鼠中發現6隻動物具肥胖和糖尿病症狀;這些公鼠再與ddY母鼠進行交配,並反覆進行數次。1992年開發出TSOD®小鼠,體重與糖尿為指標。

 

毛皮顏色

白色

 

特色

TSOD®小鼠自發性有很高機率顯現肥胖和糖尿病。TSNO®並不會顯現出肥胖或糖尿病,為TSOD®對照組動物。TSOD®小鼠為肥胖相關糖尿病疾病模式動物,其症狀條件和人類的肥胖相關型糖尿病十分相似。

 

 

Mouse
TSOD
® (Metabolic syndrome model animal)
TSNO
® (Control of TSOD®)


Origin
The origin of TSOD
® mouse is ddY mouse which comes from Doken Co., Ltd. In 1984, six animals, which were observed as obesity and diabetes, from ddY mice were accidentally discovered. With these male mice and ddY female mice, they were sibmated repeatedly. The weight and sugar in urine were assumed as indexes, and TSOD® mouse was established in 1992. In the same year, TSNO® and DIAR were also established.


Coat Color
White

Characteristics
TSOD
® mouse spontaneously indicates obesity and diabetes with high probability. On the other hand, TSNO® does not indicate obesity or diabetes and it is used as a control of TSOD®. TSOD® mouse is a model animal for obesity-related diabetes and shows conditions which are similar to obesity-related diabetes of human-beings.

 

 

 
 
 
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