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  • Response Time: <3 sec
  • Lowest Detection Limit: 0.5 nM
  • Sensitivity: 1 pA/nM
  • Application: Microvessels
  • Requires cable #91580 
  •  

    7 micron sensor with exceptional performance

    The ISO-NOP007 has a tip diameter of just 7 microns and a length of 2mm. The response is linear over a wide dynamic concentration range of NO. The design is based on a single carbon fiber coated with WPI's NO-selective membrane. A detection limit of approximately 1 nM NO makes this electrode ideal for use in tissues and microvessels. 

    The response of a 7μm NO sensor (ISO-NOP007) to successive additions of NO (100nM). Inset shows the linearity of the resulting calibration plot. 

     

    Simultaneous measurement of force (top trace) and changes of NO concentration (lower trace) in (A) the rat superior mesenteric artery relaxed with ACh and (B) a small human artery relaxed with ACh and SNAP. In this artery oxyhaemoglobin (oxyHb) partly reversed the increase in NO concentration with only a small change in force. [U. Simonsen, et al., J. Physiol., 1999, 516: 271-282.]


     


    Outside Diameter 7μm
    Available Length 2mm
    Response Time < 3 seconds
    Lowest Detection Limit/Range 0.5nM
    Nominal Sensitivity-New sensor ≥1pA/nM
    Baseline Drift none
    Poise Voltage 865mV
    Typical Quiescent Baseline Current, 25°C 300pA
    Acceptable Baseline Range 200-1500pA
    Polarization Time 1+ hours

    7363-4 Enzol Enzymatic Detergent, 1 gallon
    7364 Cidex Disinfecting Solution
    91580 Microsensor Cable
    47510 ProGuide Position/Holder with Base
    47520 ProGuide Position/Holder
    47530 ProGuide Pluse Position/Holder with fina adjustment
    47540 ProGuide Plus with Base
    SNAP25 SNAP, 25mg vial
    SNAP50 SNAP, 50mg vial
    SNAP100 SNAP, 100mg vial

     

     
     
     
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