SAM (senescence accelerated mice) inbred mice


SAMR1/TaHsd (control)


SAMR1/TaHsd (control)
來源 SAM模型是由京都大學從AKR/J開發而來。選擇了五窩嚴重老化的來進一步繁殖並檢查這些特徵。顯示正常老化的作為抗衰老系列(R系列)。由於病理結果與 AKR/J 小鼠不同,SAM 小鼠的遺傳背景受到懷疑。每個 SAM 模型在基因上都不同。每個 SAM 族群均由 Harlan 於 2002 年從武田化學有限公司 (Takeda Chemical Ltd.) 收購。
Origin SAM models were developed from AKR/J by Kyoto University. Five litters with severe senescence were selected to further propagate and examine these characteristics. Litters that showed normal aging were selected as a senescence-resistant series (R-series). The genetic background of the SAM mice became suspect after the pathological findings were different from the AKR/J mouse. Each SAM model is genetically different. Each SAM colony was acquired by Harlan from Takeda Chemical Ltd. in 2002. Harlan became Envigo in 2015, then Envigo was acquired by Inotiv in 2021.

Growth Curve成長曲線

SAM (senescence accelerated mice) inbred mice SAMR1/TaHsd (control)
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