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Model Description

  • Often used as the normotensive control for the SHR
  • Males exhibit systolic blood pressures of 125 to 140 mmHg at 10 weeks of age
  • A partially inbred model (F10) which retains some residual heterozygosity

 

Origin:

NIH received the Wistar Kyoto inbred/outbred model as an inbred from the Kyoto School of Medicine in 1971. Taconic received stock at F10 from the NIH Animal Genetic Resource in 1974. The rats were derived by caesarean in 1982 and are maintained as a randomly bred closed colony.

 

Coat Color Loci: a, Tyrc, h

 

Color: Albino

 

Species: Rat

 

Animal Diet: NIH #31M Rodent Diet

 
 
 
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